Medical Resources

At Ascend Wellness MD, we believe in reviewing the medical literature and ensuring that the treatments we recommend are backed by science. The highest quality medical research studies are often randomized controlled trials with large numbers of patients conducted at multiple sites.  Dr. Jacob reviews the literature to keep her team and you updated with publications which explain the benefits or harms of various cutting edge treatments along with the level of evidence behind the treatments. You can find some of those papers here: 

• NAD+ and its precursors in human longevity

• NAD+ and Metabolism and the control homeostasis - a balancing act between mitochondria and the nucleus

• NAD+ biosynthesis, anti-aging and disease

• Influence of NAD+ as an ageing-related immunomodulator on COVID 19 infection: A hypothesis

• NAD+ metabolism as a target for metabolic health: have we found the silver bullet?

• Emerging therapeutic roles for NAD+ metabolism in mitochondrial and  age-related disorders

• Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

• NAD and the Aging Process: Role in Life, Death and Everything in Between

• NAD Metabolism in Cancer Therapeutics

• COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity

• NAD+ and Sirtuins in Aging and Disease

• Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

• Modulating NAD+ metabolism, from bench to bedside

• Nicotinamide Riboside-The Current State of Research and Therapeutic Uses

• Sobriety and Satiety: Is NAD+ the Answer?

• NAD+ in Brain Aging and Neurodegenerative Disorders

• Platelet-rich plasma injections: an emerging therapy for chronic discogenic low back pain